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An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme
Genome-wide RNAi screening is a powerful, yet relatively immature technology that allows investigation into the role of individual genes in a process of choice. Most RNAi screens identify a large number of genes with a continuous gradient in the assessed phenotype. Screeners must then decide whether...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2956424/ https://ncbi.nlm.nih.gov/pubmed/18753689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057108323125 |
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