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An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme

Genome-wide RNAi screening is a powerful, yet relatively immature technology that allows investigation into the role of individual genes in a process of choice. Most RNAi screens identify a large number of genes with a continuous gradient in the assessed phenotype. Screeners must then decide whether...

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Detalhes bibliográficos
Main Authors: Wiles, Amy M., Ravi, Dashnamoorthy, Bhavani, Selvaraj, Bishop, Alexander J.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956424/
https://ncbi.nlm.nih.gov/pubmed/18753689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057108323125
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