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CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

Drosophila contains one (dCDK12) and humans contain two (hCDK12 and hCDK13) proteins that are the closest evolutionary relatives of yeast Ctk1, the catalytic subunit of the major elongation-phase C-terminal repeat domain (CTD) kinase in Saccharomyces cerevisiae, CTDK-I. However, until now, neither C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bartkowiak, Bartlomiej, Liu, Pengda, Phatnani, Hemali P., Fuda, Nicholas J., Cooper, Jeffrey J., Price, David H., Adelman, Karen, Lis, John T., Greenleaf, Arno L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956209/
https://ncbi.nlm.nih.gov/pubmed/20952539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1968210
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