CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1

Drosophila contains one (dCDK12) and humans contain two (hCDK12 and hCDK13) proteins that are the closest evolutionary relatives of yeast Ctk1, the catalytic subunit of the major elongation-phase C-terminal repeat domain (CTD) kinase in Saccharomyces cerevisiae, CTDK-I. However, until now, neither C...

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Hlavní autoři: Bartkowiak, Bartlomiej, Liu, Pengda, Phatnani, Hemali P., Fuda, Nicholas J., Cooper, Jeffrey J., Price, David H., Adelman, Karen, Lis, John T., Greenleaf, Arno L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956209/
https://ncbi.nlm.nih.gov/pubmed/20952539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1968210
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