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IL-1β–Mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17–Producing Cells

Regulatory T cells (Tregs) are committed to suppressive functions. Recently, it was proposed that Tregs could produce IL-17 under proinflammatory, polarizing conditions.We studied the role of Tregs on IL-17 production in the absence of exogenous cytokines and insults. Using in vitro and in vivo appr...

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Detalhes bibliográficos
Main Authors: Li, Lequn, Kim, Jin, Boussiotis, Vassiliki A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956066/
https://ncbi.nlm.nih.gov/pubmed/20817874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001536
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