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Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta.

The regulation of type 1 plasminogen activator inhibitor (PAI-1) gene expression was studied in vivo employing a murine model system. Nuclease protection analysis revealed relatively high concentrations of PAI-1 mRNA in the aorta, adipose tissue, heart, and lungs of untreated CB6 (BalbC X C57B16) mi...

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Опубликовано в: :J Clin Invest
Главные авторы: Sawdey, M S, Loskutoff, D J
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1991
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295605/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1918385/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115440
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