Tumor necrosis factor α is a key component in the obesity-linked elevation of plasminogen activator inhibitor 1

Obesity is associated with a cluster of abnormalities, including hypertension, insulin resistance, hyperinsulinemia, and elevated levels of both plasminogen activator inhibitor 1 (PAI-1) and transforming growth factor β (TGF-β). Although these changes may increase the risk for accelerated atheroscle...

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Detalhes bibliográficos
Main Authors: Samad, Fahumiya, Uysal, K. Teoman, Wiesbrock, Sarah M., Pandey, Manjula, Hotamisligil, Gökhan S., Loskutoff, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22014/
https://ncbi.nlm.nih.gov/pubmed/10359811
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