Rapid ischemic tolerance induced by adenosine preconditioning results in Bcl-2 interacting mediator of cell death (Bim) degradation by the proteasome

Rapid ischemic tolerance, induced one hour following ischemic preconditioning, is mediated via the ubiq-uitin-proteasome system and the degradation of the pro-apoptotic bcl-2 family protein Bim. Previous studies implicate adenosine A1 receptors in mediating rapid ischemic tolerance. Since the A1 ade...

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Hlavní autoři: Ordonez, Andrea Nicole, Jessick, Veronica Joy, Clayton, Corrin Erin, Ashley, Michelle Dawn, Thompson, Simon John, Simon, Roger Pancoast, Meller, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: e-Century Publishing Corporation 2010
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955863/
https://ncbi.nlm.nih.gov/pubmed/20957068
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