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Folding, DNA recognition and function of GIY-YIG endonucleases: crystal structures of R.Eco29kI

The GIY-YIG endonuclease family comprises hundreds of diverse proteins and a multitude of functions; none have been visualized bound to DNA. The structure of the GIY-YIG restriction endonuclease R.Eco29kI has been solved both alone and bound to its target site. The protein displays a domain-swapped...

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Bibliografiske detaljer
Main Authors: Mak, Amanda Nga-Sze, Lambert, Abigail R., Stoddard, Barry L.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955809/
https://ncbi.nlm.nih.gov/pubmed/20800503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.07.006
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