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A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells

The NADPH oxidase (Nox) proteins catalyze the regulated formation of reactive oxygen species (ROS) which play key roles as signaling molecules in several physiological and pathophysiological processes. ROS generation by the Nox1 member of the Nox family is necessary for the formation of extracellula...

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Detalhes bibliográficos
Main Authors: Gianni, Davide, Taulet, Nicolas, Zhang, Hui, DerMardirossian, Celine, Kister, Jeremy, Martinez, Luis, Roush, William R., Brown, Steve J., Bokoch, Gary M., Rosen, Hugh
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955773/
https://ncbi.nlm.nih.gov/pubmed/20715845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100219n
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