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Large-Scale Analysis of Orthologs and Paralogs under Covarion-Like and Constant-but-Different Models of Amino Acid Evolution
Functional divergence between homologous proteins is expected to affect amino acid sequences in two main ways, which can be considered as proxies of biochemical divergence: a “covarion-like” pattern of correlated changes in evolutionary rates, and switches in conserved residues (“conserved but diffe...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2010
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955734/ https://ncbi.nlm.nih.gov/pubmed/20551039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq149 |
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