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Tissue-Specificity of Gene Expression Diverges Slowly between Orthologs, and Rapidly between Paralogs

The ortholog conjecture implies that functional similarity between orthologous genes is higher than between paralogs. It has been supported using levels of expression and Gene Ontology term analysis, although the evidence was rather weak and there were also conflicting reports. In this study on 12 s...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Kryuchkova-Mostacci, Nadezda, Robinson-Rechavi, Marc
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193323/
https://ncbi.nlm.nih.gov/pubmed/28030541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005274
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