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Tissue-Specificity of Gene Expression Diverges Slowly between Orthologs, and Rapidly between Paralogs

The ortholog conjecture implies that functional similarity between orthologous genes is higher than between paralogs. It has been supported using levels of expression and Gene Ontology term analysis, although the evidence was rather weak and there were also conflicting reports. In this study on 12 s...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Kryuchkova-Mostacci, Nadezda, Robinson-Rechavi, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5193323/
https://ncbi.nlm.nih.gov/pubmed/28030541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005274
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