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Analysis of a DNA simulation model through hairpin melting experiments

We compare the predictions of a two-bead Brownian dynamics simulation model to melting experiments of DNA hairpins with complementary AT or GC stems and noninteracting loops in buffer A. This system emphasizes the role of stacking and hydrogen bonding energies, which are characteristics of DNA, rath...

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Autori principali: Linak, Margaret C., Dorfman, Kevin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Institute of Physics 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955729/
https://ncbi.nlm.nih.gov/pubmed/20886965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3480685
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