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Bioreducible Liposomes for Gene Delivery: From the Formulation to the Mechanism of Action
BACKGROUND: A promising strategy to create stimuli-responsive gene delivery systems is to exploit the redox gradient between the oxidizing extracellular milieu and the reducing cytoplasm in order to disassemble DNA/cationic lipid complexes (lipoplexes). On these premises, we previously described the...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955545/ https://ncbi.nlm.nih.gov/pubmed/20976172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013430 |
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