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Increasing the power of identifying gene × gene interactions in genome-wide association studies

In this paper we investigate the power to identify gene × gene interactions in genome-wide association studies. In our analysis we focus on two-stage analyses: analyses in which we only test for interactions between SNPs that show some marginal effect. We give two algorithms to compute significance...

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Hlavní autoři: Kooperberg, Charles, LeBlanc, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955421/
https://ncbi.nlm.nih.gov/pubmed/18200600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20300
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