Mesenchymal Stem Cell Mechanics from the Attached to the Suspended State

Human mesenchymal stem cells (hMSCs) are therapeutically useful cells that are typically expanded in vitro on stiff substrata before reimplantation. Here we explore MSC mechanical and structural changes via atomic force microscopy and optical stretching during extended passaging, and we demonstrate...

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Detalhes bibliográficos
Main Authors: Maloney, John M., Nikova, Dessy, Lautenschläger, Franziska, Clarke, Emer, Langer, Robert, Guck, Jochen, Van Vliet, Krystyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Cellular Biophysics and Electrophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955350/
https://ncbi.nlm.nih.gov/pubmed/20959088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.052
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