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A Lattice Model for Transcription Factor Access to Nucleosomal DNA

Nucleosomes, the basic repeating unit of chromatin, consist of 147 basepairs of DNA that are wrapped in almost two turns around a histone protein octamer core. Because ∼3/4 of the human genomic DNA is found within nucleosomes, their position and DNA interaction is an essential determinant for the DN...

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Autors principals: Teif, Vladimir B., Ettig, Ramona, Rippe, Karsten
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955348/
https://ncbi.nlm.nih.gov/pubmed/20959101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.019
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