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Ligand-Induced DNA Condensation: Choosing the Model
We test and compare different models for ligand-induced DNA condensation. Using (14)C-labeled spermidine(3+), we measure the binding to condensed DNA at micromolar to molar polyamine concentrations. DNA aggregates at a critical polyamine concentration. Spermidine(3+) binding becomes highly cooperati...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2005
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366757/ https://ncbi.nlm.nih.gov/pubmed/16085765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063909 |
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