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Ligand-Induced DNA Condensation: Choosing the Model

We test and compare different models for ligand-induced DNA condensation. Using (14)C-labeled spermidine(3+), we measure the binding to condensed DNA at micromolar to molar polyamine concentrations. DNA aggregates at a critical polyamine concentration. Spermidine(3+) binding becomes highly cooperati...

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Bibliografiske detaljer
Hovedforfatter: Teif, Vladimir B.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366757/
https://ncbi.nlm.nih.gov/pubmed/16085765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063909
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