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Dynamic instability of genomic methylation patterns in pluripotent stem cells

BACKGROUND: Genomic methylation patterns are established during gametogenesis, and perpetuated in somatic cells by faithful maintenance methylation. There have been previous indications that genomic methylation patterns may be less stable in embryonic stem (ES) cells than in differentiated somatic c...

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Main Authors: Ooi, Steen KT, Wolf, Daniel, Hartung, Odelya, Agarwal, Suneet, Daley, George Q, Goff, Stephen P, Bestor, Timothy H
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954997/
https://ncbi.nlm.nih.gov/pubmed/20868487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-3-17
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