Cytokine regulation of immunoglobulin secretion by neonatal lymphocytes.
In contrast to adult lymphocytes, neonatal lymphocytes secrete minimal amounts of Ig in response to stimulation with immobilized MAb to CD3. This deficiency could be overcome by the addition of supplemental IL-2, IL-4, or IL-6, resulting in the secretion of all Ig isotypes. There were no major diffe...
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| Udgivet i: | J Clin Invest |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295498/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1832176/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115400 |
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