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Aggregation of cellular prion protein is initiated by proximity-induced dimerization

Prion diseases or transmissible spongiform encephalopathies (TSEs) are infectious and fatal neurodegenerative disorders in humans and animals. Pathological features of TSEs include the conversion of cellular prion protein (PrP(C)) into an altered disease-associated conformation generally designated...

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Bibliografiska uppgifter
Huvudupphovsmän: Goggin, Kevin, Bissonnette, Cyntia, Grenier, Catherine, Volkov, Leonid, Roucou, Xavier
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954962/
https://ncbi.nlm.nih.gov/pubmed/17663754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.04611.x
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