Aggresomes do not represent a general cellular response to protein misfolding in mammalian cells

BACKGROUND: Aggresomes are juxtanuclear inclusion bodies that have been proposed to represent a general cellular response to misfolded proteins in mammalian cells. Yet, why aggresomes are not a pathological characteristic of protein misfolding diseases is unclear. Here, we investigate if a misfolded...

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Bibliografiske detaljer
Main Authors: Beaudoin, Simon, Goggin, Kevin, Bissonnette, Cyntia, Grenier, Catherine, Roucou, Xavier
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576168/
https://ncbi.nlm.nih.gov/pubmed/18937858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-9-59
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