Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases. Quercetin, a plant flavonoid, is a potent antioxida...

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Main Authors: Ganesan, Shyamala, Faris, Andrea N, Comstock, Adam T, Chattoraj, Sangbrita S, Chattoraj, Asamanja, Burgess, John R, Curtis, Jeffrey L, Martinez, Fernando J, Zick, Suzanna, Hershenson, Marc B, Sajjan, Uma S
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954923/
https://ncbi.nlm.nih.gov/pubmed/20920189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-131
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