Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is characterized by chronic bronchitis, emphysema and irreversible airflow limitation. These changes are thought to be due to oxidative stress and an imbalance of proteases and antiproteases. Quercetin, a plant flavonoid, is a potent antioxida...

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Bibliografiske detaljer
Main Authors: Ganesan, Shyamala, Faris, Andrea N, Comstock, Adam T, Chattoraj, Sangbrita S, Chattoraj, Asamanja, Burgess, John R, Curtis, Jeffrey L, Martinez, Fernando J, Zick, Suzanna, Hershenson, Marc B, Sajjan, Uma S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954923/
https://ncbi.nlm.nih.gov/pubmed/20920189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-131
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