4-oxo-N-(4-hydroxyphenyl)retinamide: Two Independent Ways to Kill Cancer Cells

BACKGROUND: The retinoid 4-oxo-N-(4-hydroxyphenyl)retinamide (4-oxo-4-HPR) is a polar metabolite of fenretinide (4-HPR) very effective in killing cancer cells of different histotypes, able to inhibit 4-HPR-resistant cell growth and to act synergistically in combination with the parent drug. Unlike 4...

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Hlavní autoři: Tiberio, Paola, Cavadini, Elena, Abolafio, Gabriella, Formelli, Franca, Appierto, Valentina
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954786/
https://ncbi.nlm.nih.gov/pubmed/20976277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013362
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