Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.
To make synthetic peptide vaccines effective in a broad population of outbred humans, one would have to incorporate enough antigenic determinants to elicit recognition by T cells of most HLA types. We have previously defined multideterminant regions of the human immunodeficiency virus (HIV) envelope...
Shranjeno v:
| izdano v: | J Clin Invest |
|---|---|
| Principais autores: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
1991
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295474/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1715888/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115389 |
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