Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.

To make synthetic peptide vaccines effective in a broad population of outbred humans, one would have to incorporate enough antigenic determinants to elicit recognition by T cells of most HLA types. We have previously defined multideterminant regions of the human immunodeficiency virus (HIV) envelope...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Berzofsky, J A, Pendleton, C D, Clerici, M, Ahlers, J, Lucey, D R, Putney, S D, Shearer, G M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295474/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1715888/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115389
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