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Epigenetic Changes Coincide with in Vitro Primate GnRH Neuronal Maturation

Cellular and molecular mechanisms underlying pulsatile GnRH release are not well understood. In the present study, we examined the developmental changes in intracellular calcium dynamics, peptide release, gene expression, and DNA methylation in cultured GnRH neurons derived from the nasal placode of...

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Hlavní autoři: Kurian, Joseph R., Keen, Kim L., Terasawa, Ei
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954729/
https://ncbi.nlm.nih.gov/pubmed/20861233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0555
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