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Epigenetic Changes Coincide with in Vitro Primate GnRH Neuronal Maturation

Cellular and molecular mechanisms underlying pulsatile GnRH release are not well understood. In the present study, we examined the developmental changes in intracellular calcium dynamics, peptide release, gene expression, and DNA methylation in cultured GnRH neurons derived from the nasal placode of...

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Detalhes bibliográficos
Main Authors: Kurian, Joseph R., Keen, Kim L., Terasawa, Ei
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954729/
https://ncbi.nlm.nih.gov/pubmed/20861233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0555
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