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Epigenetic Changes Coincide with in Vitro Primate GnRH Neuronal Maturation

Cellular and molecular mechanisms underlying pulsatile GnRH release are not well understood. In the present study, we examined the developmental changes in intracellular calcium dynamics, peptide release, gene expression, and DNA methylation in cultured GnRH neurons derived from the nasal placode of...

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Autori principali: Kurian, Joseph R., Keen, Kim L., Terasawa, Ei
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954729/
https://ncbi.nlm.nih.gov/pubmed/20861233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0555
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