Beneficial Metabolic Effects Caused by Persistent Activation of β-Cell M(3) Muscarinic Acetylcholine Receptors in Transgenic Mice

Previous studies have shown that β-cell M(3) muscarinic acetylcholine receptors (M3Rs) play a key role in maintaining blood glucose homeostasis by enhancing glucose-dependent insulin release. In this study, we tested the hypothesis that long-term, persistent activation of β-cell M3Rs can improve glu...

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Autors principals: Gautam, Dinesh, de Azua, Inigo Ruiz, Li, Jian Hua, Guettier, Jean-Marc, Heard, Thomas, Cui, Yinghong, Lu, Huiyan, Jou, William, Gavrilova, Oksana, Zawalich, Walter S., Wess, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954720/
https://ncbi.nlm.nih.gov/pubmed/20843999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0519
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