Specific Patterns of Cdc42 Activity Are Related to Distinct Elements of T Cell Polarization

T cell polarization toward and within the cellular interface with an APC is critical for effective T cell activation. The Rho family GTPase Cdc42 is a central regulator of cellular polarization. Using live-cell imaging, we characterized the spatiotemporal patterns of Cdc42 activity and their physiol...

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Hlavní autoři: Tskvitaria-Fuller, Irina, Seth, Abhinav, Mistry, Neeta, Gu, Hua, Rosen, Michael K., Wülfing, Christoph
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954656/
https://ncbi.nlm.nih.gov/pubmed/16849480
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