Učitavanje...
Oxidative Stress Stimulates Apoptosis and Activates NF-κB in Osteoblastic Cells via a PKCβ/p66(shc) Signaling Cascade: Counter Regulation by Estrogens or Androgens
Aging or acute loss of estrogens or androgens increases the levels of reactive oxygen species, activates nuclear factor-κB (NF-κB), and promotes the phosphorylation of p66(shc), a redox enzyme that amplifies mitochondrial reactive oxygen species generation and stimulates apoptosis. We report that in...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Endocrine Society
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954638/ https://ncbi.nlm.nih.gov/pubmed/20685851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0189 |
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