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Antagonism of Δ(9)-THC induced behavioral effects by rimonabant: time-course studies in rats

The objective was to examine the time-course of the cannabinoid 1 receptor antagonist/inverse agonist rimonabant’s ability to antagonize in vivo cannabinergic agonist effects. We used two behavioral procedures sensitive to the effects of Δ(9)-tetrahydrocannabinol (Δ(9)-THC): rat drug discrimination...

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Main Authors: Järbe, Torbjörn U.C., Gifford, Roger S., Makriyannis, Alexandros
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954612/
https://ncbi.nlm.nih.gov/pubmed/20854804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.09.006
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