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Impact of metabotropic glutamate 2/3 receptor stimulation on activated dopamine release and locomotion

RATIONALE: Activation of metabotropic glutamate (mGlu) 2/3 receptors may provide a novel strategy for treating schizophrenia. This effect is thought to be mediated through dopamine-independent mechanisms because mGlu2/3-receptor agonists have no considerable affinity for dopamine receptors. These ag...

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Detalhes bibliográficos
Main Authors: Pehrson, Alan L., Moghaddam, Bita
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954604/
https://ncbi.nlm.nih.gov/pubmed/20585759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1914-8
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