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Activation of type 5 metabotropic glutamate receptors attenuates deficits in cognitive flexibility induced by NMDA receptor blockade

Metabotropic glutamate (mGlu) receptors provide a mechanism by which the function of NMDA glutamate receptors can be modulated. As NMDA receptor hypofunction is implicated in the etiology of psychiatric disorders, including schizophrenia, the pharmacological regulation of mGlu receptor activity repr...

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Autors principals: Stefani, Mark R., Moghaddam, Bita
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359134/
https://ncbi.nlm.nih.gov/pubmed/20371234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.01.028
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