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Intra-islet insulin permits glucose to directly suppress pancreatic A cell function.

Inhibition of pancreatic glucagon secretion during hyperglycemia could be mediated by (a) glucose, (b) insulin, (c) somatostatin, or (d) glucose in conjunction with insulin. To determine the role of these factors in the mediation of glucagon suppression, we injected alloxan while clamping the arteri...

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Bibliographic Details
Main Authors: Greenbaum, C J, Havel, P J, Taborsky, G J, Klaff, L J
Format: Artigo
Language:Inglês
Published: 1991
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC295460/
https://ncbi.nlm.nih.gov/pubmed/1679440
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