Novel characteristics of a trafficking-defective G572R-hERG channel linked to hereditary long QT syndrome

BACKGROUND: The congenital long QT syndrome is a heterogeneous genetic disease associated with delayed cardiac repolarization, prolonged QT intervals, the development of ventricular arrhythmias and sudden death. Type 2 congenital long QT syndrome (LQT2) results from KCNH2 or hERG gene mutations. hER...

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Detalhes bibliográficos
Main Authors: Lian, Jiangfang, Huang, Na, Zhou, JunBo, Ge, ShiJun, Huang, XiaoYan, Huo, JianHua, Liu, Liying, Xu, WeiFeng, Zhang, Shun, Yang, Xi, Zhou, JianQing, Huang, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: Pulsus Group Inc 2010
Assuntos:
Experimental Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954534/
https://ncbi.nlm.nih.gov/pubmed/20931094
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