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Localization of heparin-binding EGF-like growth factor in the smooth muscle cells and macrophages of human atherosclerotic plaques.

Heparin-binding EGF-like growth factor (HB-EGF) is a potent chemoattractant and mitogen for smooth muscle cells (SMC) in culture. To elucidate whether HB-EGF is implicated in the pathogenesis of human atherosclerosis, we examined immunohistochemical localization of HB-EGF in human aortic walls and a...

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Published in:J Clin Invest
Main Authors: Miyagawa, J, Higashiyama, S, Kawata, S, Inui, Y, Tamura, S, Yamamoto, K, Nishida, M, Nakamura, T, Yamashita, S, Matsuzawa, Y
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1995
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7814641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117669
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