Atherosclerotic plaque-derived extracellular vesicles mediate smooth muscle cell phenotypic switching and promote vascular remodeling

Abstract Background Despite the use of lipid-lowering and anti-inflammatory treatments, the progression of atherosclerosis is relentless in most patients. This suggests the presence of in situ pathological factors that continuously exacerbate lesions. We hypothesized that extracellular vesicles (EVs...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Jia Wang, Xuan Shi, Di Wang, Jie Gao, Kangmo Huang, Juanji Li, Weichen Dong, Yunzi Li, Hongquan Guo, Yi Wang, Zhenqian Huang, Zhihui Liu, Li Huang, Liangyuan Pan, Xinfeng Liu, Wusheng Zhu, Mengna Peng, Gelin Xu
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Springer 2026-03-01
Rangatū:	Cellular and Molecular Life Sciences
Ngā marau:	Carotid atherosclerosis MiRNAs Myl12b Tissue EVs
Urunga tuihono:	https://doi.org/10.1007/s00018-026-06094-4
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!