Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

HIV-1 specific HLA-B-restricted CD8+ T cell responses differ from HLA-C-restricted responses in antiviral effectiveness. To investigate possible reasons for these differences, we characterized the frequency and polyfunctionality of immmunodominant HLA-B*57/B5801- and HLA-Cw*07-restricted CD8+ T cell...

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Bibliografiske detaljer
Main Authors: Mkhwanazi, Nompumelelo, Thobakgale, Christina F., van der Stok, Mary, Reddy, Shabashini, Mncube, Zenele, Chonco, Fundisiwe, Walker, Bruce D., Altfeld, Marcus, Goulder, Philip J.R., Ndung'u, Thumbi
Format: Artigo
Sprog:Inglês
Udgivet: Academic Press 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954365/
https://ncbi.nlm.nih.gov/pubmed/20638093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.06.002
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