The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation

Proteins with the DUF2063 domain constitute a new Pfam family, PF09836. The crystal structure of a member of this family, NGO1945 from Neisseria gonorrhoeae, has been determined and reveals that the N-terminal DUF2063 domain is likely to be a DNA-binding domain. In conjunction with the rest of the p...

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Hlavní autoři: Das, Debanu, Grishin, Nick V., Kumar, Abhinav, Carlton, Dennis, Bakolitsa, Constantina, Miller, Mitchell D., Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Burra, Prasad, Chen, Connie, Chiu, Hsiu-Ju, Chiu, Michelle, Clayton, Thomas, Deller, Marc C., Duan, Lian, Ellrott, Kyle, Ernst, Dustin, Farr, Carol L., Feuerhelm, Julie, Grzechnik, Anna, Grzechnik, Slawomir K., Grant, Joanna C., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Johnson, Hope A., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Krishna, S. Sri, Marciano, David, McMullan, Daniel, Morse, Andrew T., Nigoghossian, Edward, Nopakun, Amanda, Okach, Linda, Oommachen, Silvya, Paulsen, Jessica, Puckett, Christina, Reyes, Ron, Rife, Christopher L., Sefcovic, Natasha, Tien, Henry J., Trame, Christine B., van den Bedem, Henry, Weekes, Dana, Wooten, Tiffany, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2009
Témata:
Domains of Unknown Function
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954202/
https://ncbi.nlm.nih.gov/pubmed/20944208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109022672
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