The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation

Proteins with the DUF2063 domain constitute a new Pfam family, PF09836. The crystal structure of a member of this family, NGO1945 from Neisseria gonorrhoeae, has been determined and reveals that the N-terminal DUF2063 domain is likely to be a DNA-binding domain. In conjunction with the rest of the p...

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Autors principals: Das, Debanu, Grishin, Nick V., Kumar, Abhinav, Carlton, Dennis, Bakolitsa, Constantina, Miller, Mitchell D., Abdubek, Polat, Astakhova, Tamara, Axelrod, Herbert L., Burra, Prasad, Chen, Connie, Chiu, Hsiu-Ju, Chiu, Michelle, Clayton, Thomas, Deller, Marc C., Duan, Lian, Ellrott, Kyle, Ernst, Dustin, Farr, Carol L., Feuerhelm, Julie, Grzechnik, Anna, Grzechnik, Slawomir K., Grant, Joanna C., Han, Gye Won, Jaroszewski, Lukasz, Jin, Kevin K., Johnson, Hope A., Klock, Heath E., Knuth, Mark W., Kozbial, Piotr, Krishna, S. Sri, Marciano, David, McMullan, Daniel, Morse, Andrew T., Nigoghossian, Edward, Nopakun, Amanda, Okach, Linda, Oommachen, Silvya, Paulsen, Jessica, Puckett, Christina, Reyes, Ron, Rife, Christopher L., Sefcovic, Natasha, Tien, Henry J., Trame, Christine B., van den Bedem, Henry, Weekes, Dana, Wooten, Tiffany, Xu, Qingping, Hodgson, Keith O., Wooley, John, Elsliger, Marc-André, Deacon, Ashley M., Godzik, Adam, Lesley, Scott A., Wilson, Ian A.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2009
Matèries:
Domains of Unknown Function
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954202/
https://ncbi.nlm.nih.gov/pubmed/20944208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109022672
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