The Cytoplasmic Tail of the T Cell Receptor CD3 ε Subunit Contains a Phospholipid-Binding Motif that Regulates T Cell Functions

The CD3 ε subunit of the TCR complex contains two defined signaling domains, a proline-rich sequence and an ITAM. We identified a third signaling sequence in CD3 ε, termed the basic-rich stretch (BRS). Herein, we show that the positively charged residues of the BRS enable this region of CD3 ε to com...

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Detaylı Bibliyografya
Asıl Yazarlar: DeFord-Watts, Laura M., Tassin, Tara C., Becker, Amy M., Medeiros, Jennifer J., Albanesi, Joseph P., Love, Paul E., Wülfing, Christoph, van Oers, Nicolai S. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954055/
https://ncbi.nlm.nih.gov/pubmed/19542373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900404
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