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A Quantitative Proteomics Design for Systematic Identification of Protease Cleavage Events
We present here a novel proteomics design for systematic identification of protease cleavage events by quantitative N-terminal proteomics, circumventing the need for time-consuming manual validation. We bypass the singleton detection problem of protease-generated neo-N-terminal peptides by introduci...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953924/ https://ncbi.nlm.nih.gov/pubmed/20627866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M110.001271 |
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