Thymic and peripheral microenvironments differentially mediate development and maturation of iNKT cells by IL-15 transpresentation

Invariant NKT (iNKT) cells are an innate type of T cells, which respond rapidly on activation. iNKT cells acquire these innate-like abilities during development; however, the signals driving development and functional maturation remain only partially understood. Because interleukin-15 (IL-15) is cru...

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Bibliografiske detaljer
Main Authors: Castillo, Eliseo F., Acero, Luis F., Stonier, Spencer W., Zhou, Dapeng, Schluns, Kimberly S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Immunobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953886/
https://ncbi.nlm.nih.gov/pubmed/20581314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-277103
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