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Visualizing one-dimensional diffusion of eukaryotic DNA repair factors along a chromatin lattice
DNA-binding proteins survey genomes for targets using facilitated diffusion, which typically includes a one-dimensional (1D) scanning component for sampling local regions. Eukaryotic proteins must accomplish this task while navigating through chromatin. Yet it is unknown whether nucleosomes disrupt...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953804/ https://ncbi.nlm.nih.gov/pubmed/20657586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1858 |
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