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Development of a Nascent Galectin-1 Chimeric Molecule for Studying the Role of Leukocyte Galectin-1 Ligands and Immune Disease Modulation

Galectin-1 (Gal-1), a β-galactoside–binding lectin, plays a profound role in modulating adaptive immune responses by altering the phenotype and fate of T cells. Experimental data showing recombinant Gal-1 (rGal-1) efficacy on T cell viability and cytokine production, nevertheless, is controversial d...

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Main Authors: Cedeno-Laurent, Filiberto, Barthel, Steven R., Opperman, Matthew J., Lee, David M., Clark, Rachael A., Dimitroff, Charles J.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953643/
https://ncbi.nlm.nih.gov/pubmed/20844192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000715
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