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Secretion of insulinlike growth factor I and insulinlike growth factor-binding proteins by murine bone marrow stromal cells.

Insulin-like growth factor I (IGF-I) stimulates hematopoiesis. We examined whether bone marrow stromal cells synthesize IGF-I. Secretion of IGF-I immunoreactivity by cells from TC-1 murine bone marrow stromal cells was time-dependent and inhibited by cycloheximide. Gel filtration chromatography unde...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Abboud, S L, Bethel, C R, Aron, D C
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295364/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1713920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115327
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