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Monitoring Molecular-Specific Pharmacodynamics of Rapamycin in Vivo with Inducible Gal4→ Fluc Transgenic Reporter Mice
Rapamycin (Rap), a small molecule inhibitor of mTOR, is an immunosuppressant and several Rap analogs are cancer chemotherapeutics. Further pharmacological development will be significantly facilitated if in vivo reporter models are available to enable monitoring of molecular-specific pharmacodynamic...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953587/ https://ncbi.nlm.nih.gov/pubmed/20858726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0265 |
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