Reduced expression and activation of voltage-gated sodium channels contributes to blunted baroreflex sensitivity in heart failure rats

Voltage-gated sodium (Na(v)) channels are responsible for initiation and propagation of action potential in the neurons. To explore the mechanisms for chronic heart failure (CHF)-induced baroreflex dysfunction, we measured the expression and current density of Na(v) channel subunits (Na(v)1.7, Na(v)...

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Bibliographic Details
Main Authors: Tu, Huiyin, Zhang, Libin, Tran, Thai P., Muelleman, Robert L., Li, Yu-Long
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953570/
https://ncbi.nlm.nih.gov/pubmed/20857502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22483
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