Abnormalities in Oxygen Sensing Define Early and Late Onset Preeclampsia as Distinct Pathologies

BACKGROUND: The pathogenesis of preeclampsia, a serious pregnancy disorder, is still elusive and its treatment empirical. Hypoxia Inducible Factor-1 (HIF-1) is crucial for placental development and early detection of aberrant regulatory mechanisms of HIF-1 could impact on the diagnosis and managemen...

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Main Authors: Rolfo, Alessandro, Many, Ariel, Racano, Antonella, Tal, Reshef, Tagliaferro, Andrea, Ietta, Francesca, Wang, Jinxia, Post, Martin, Caniggia, Isabella
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953500/
https://ncbi.nlm.nih.gov/pubmed/20967267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013288
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